Recent Publications

  1. Zhang R, Hua G, Andacht TM, and Adang MJ. A 106-kDa Aminopeptidase Is a Putative Receptor for Bacillus thuringiensis Cry11Ba Toxin in the Mosquito Anopheles gambiae. Biochemistry 47: 11263-11272, 2008.

  2. Hua G, Zhang R, Abdullah MA, and Adang MJ. Anopheles gambiae cadherin AgCad1 binds the Cry4Ba toxin of Bacillus thuringiensis israelensis and a fragment of AgCad1 synergizes toxicity. Biochemistry 47: 5101-5110, 2008.

  3. Krishnamoorthy M, Jurat-Fuentes JL, McNall RJ, Andacht T, and Adang MJ. Identification of novel Cry1Ac binding proteins in midgut membranes from Heliothis virescens using proteomic analyses. Insect Biochem Mol Biol 37: 189-201, 2007.

  4. Karumbaiah L, Oppert B, Jurat-Fuentes JL, and Adang MJ. Analysis of midgut proteinases from Bacillus thuringiensis-susceptible and -resistant Heliothis virescens (Lepidoptera: Noctuidae). Comp Biochem Physiol B Biochem Mol Biol 146: 139-146, 2007.

  5. Jurat-Fuentes JL and Adang MJ. A proteomic approach to study Cry1Ac binding proteins and their alterations in resistant Heliothis virescens larvae. J Invertebr Pathol 95: 187-191, 2007.

  6. Chen J, Hua G, Jurat-Fuentes JL, Abdullah MA, and Adang MJ. Synergism of Bacillus thuringiensis toxins by a fragment of a toxin-binding cadherin. Proc Natl Acad Sci U S A 104: 13901-13906, 2007.

  7. Jurat-Fuentes JL and Adang MJ. Cry toxin mode of action in susceptible and resistant Heliothis virescens larvae. J Invertebr Pathol 92: 166-171, 2006.

  8. Jurat-Fuentes JL and Adang MJ. The Heliothis virescens cadherin protein expressed in Drosophila S2 cells functions as a receptor for Bacillus thuringiensis Cry1A but not Cry1Fa toxins. Biochemistry 45: 9688-9695, 2006.

  9. Griffitts JS, Haslam SM, Yang T, Garczynski SF, Mulloy B, Morris H, Cremer PS, Dell A, Adang MJ, and Aroian RV. Glycolipids as receptors for Bacillus thuringiensis crystal toxin. Science 307: 922-925, 2005.

  10. Chen J, Brown MR, Hua G, and Adang MJ. Comparison of the localization of Bacillus thuringiensis Cry1A delta-endotoxins and their binding proteins in larval midgut of tobacco hornworm, Manduca sexta. Cell Tissue Res 321: 123-129, 2005.

  11. Jurat-Fuentes JL, Gahan LJ, Gould FL, Heckel DG, and Adang MJ. The HevCaLP protein mediates binding specificity of the Cry1A class of Bacillus thuringiensis toxins in Heliothis virescens. Biochemistry 43: 14299-14305, 2004.

  12. Jurat-Fuentes JL and Adang MJ. Characterization of a Cry1Ac-receptor alkaline phosphatase in susceptible and resistant Heliothis virescens larvae. Eur J Biochem 271: 3127-3135, 2004.

  13. Hua G, Jurat-Fuentes JL, and Adang MJ. Fluorescent-based assays establish Manduca sexta Bt-R(1a) cadherin as a receptor for multiple Bacillus thuringiensis Cry1A toxins in Drosophila S2 cells. Insect Biochem Mol Biol 34: 193-202, 2004.

  14. Hua G, Jurat-Fuentes JL, and Adang MJ. Bt-R1a extracellular cadherin repeat 12 mediates Bacillus thuringiensis Cry1Ab binding and cytotoxicity. J Biol Chem 279: 28051-28056, 2004.

  15. McNall RJ and Adang MJ. Identification of novel Bacillus thuringiensis Cry1Ac binding proteins in Manduca sexta midgut through proteomic analysis. Insect Biochem Mol Biol 33: 999-1010, 2003.

  16. Jurat-Fuentes JL, Gould FL, and Adang MJ. Dual resistance to Bacillus thuringiensis Cry1Ac and Cry2Aa toxins in Heliothis virescens suggests multiple mechanisms of resistance. Appl Environ Microbiol 69: 5898-5906, 2003.

  17. Banks DJ, Hua G, and Adang MJ. Cloning of a Heliothis virescens 110 kDa aminopeptidase N and expression in Drosophila S2 cells. Insect Biochem Mol Biol 33: 499-508, 2003.

  18. Abdullah MA, Alzate O, Mohammad M, McNall RJ, Adang MJ, and Dean DH. Introduction of Culex toxicity into Bacillus thuringiensis Cry4Ba by protein engineering. Appl Environ Microbiol 69: 5343-5353, 2003.

  19. Masson L, Mazza A, Sangadala S, Adang MJ, and Brousseau R. Polydispersity of Bacillus thuringiensis Cry1 toxins in solution and its effect on receptor binding kinetics. Biochim Biophys Acta 1594: 266-275, 2002.

  20. Jurat-Fuentes JL, Gould FL, and Adang MJ. Altered Glycosylation of 63- and 68-kilodalton microvillar proteins in Heliothis virescens correlates with reduced Cry1 toxin binding, decreased pore formation, and increased resistance to Bacillus thuringiensis Cry1 toxins. Appl Environ Microbiol 68: 5711-5717, 2002.

  21. Daniel A, Sangadala S, Dean DH, and Adang MJ. Denaturation of either Manduca sexta aminopeptidase N or Bacillus thuringiensis Cry1A toxins exposes binding epitopes hidden under nondenaturing conditions. Appl Environ Microbiol 68: 2106-2112, 2002.

  22. Sangadala S, Azadi P, Carlson R, and Adang MJ. Carbohydrate analyses of Manduca sexta aminopeptidase N, co-purifying neutral lipids and their functional interactions with Bacillus thuringiensis Cry1Ac toxin. Insect Biochem Mol Biol 32: 97-107, 2001.

  23. Lee MK, Jenkins JL, You TH, Curtiss A, Son JJ, Adang MJ, and Dean DH. Mutations at the arginine residues in alpha8 loop of Bacillus thuringiensis delta-endotoxin Cry1Ac affect toxicity and binding to Manduca sexta and Lymantria dispar aminopeptidase N. FEBS Lett 497: 108-112, 2001.

  24. Jurat-Fuentes JL and Adang MJ. Importance of Cry1 delta-endotoxin domain II loops for binding specificity in Heliothis virescens (L.). Appl Environ Microbiol 67: 323-329, 2001.

  25. Hua G, Masson L, Jurat-Fuentes JL, Schwab G, and Adang MJ. Binding analyses of Bacillus thuringiensis Cry delta-endotoxins using brush border membrane vesicles of Ostrinia nubilalis. Appl Environ Microbiol 67: 872-879, 2001.

  26. Banks DJ, Jurat-Fuentes JL, Dean DH, and Adang MJ. Bacillus thuringiensis Cry1Ac and Cry1Fa delta-endotoxin binding to a novel 110 kDa aminopeptidase in Heliothis virescens is not N-acetylgalactosamine mediated. Insect Biochem Mol Biol 31: 909-918, 2001.